Kit format: 1 x 96 wells
Measurement range: 3 – 300 pmol/L (24 – 2400 pg/mL)
Highly specific, sensitive and rapid method for determination of glicentin
No cross-reactivity to circulating proglucagon derived gut peptides
Assay buffers and calibrators have been optimized to prevent degradation and aggregation of glicentin
The Mercodia Glicentin ELISA is a high-quality immunoassay for the quantification of human glicentin in serum, plasma, and cell culture media.
Glicentin is a proglucagon-derived gut peptide that is released in the gut in response to feed intake. It is present in high levels in the circulation after stimulation and is often a problem when measuring glucagon and other proglucagon derivates because of its shared sequence. The Mercodia Glicentin ELISA however, has no cross-reactivity to such circulating proglucagon-derived gut peptides.
Want to read more about our Glicentin ELISA and other Mercodia ELISAs, see this White Paper.
Serum, EDTA plasma and cell culture media
3 - 300 pmol/L (24-2400 pg/mL)
≤3 pmol/L (24 pg/mL)
1 h + 1 h + 15 min
The following cross-reactions have been tested:
For other languages and older versions:Technical Library
Manell, H. et al. (2016) Altered Plasma Levels of Glucagon, GLP-1 and Glicentin During OGTT in Adolescents With Obesity and Type 2 Diabetes. J Clin Endocrinol Metab 101, 1181–1189. Read more >
Raffort, J. et al. (2017) Fasting Circulating Glicentin Increases After Bariatric Surgery.Obes. Surg. 27, 1581–1588. Read more >
Poitou, C. et al. (2018) Fasting levels of glicentin are higher in Roux-en-Y gastric bypass patients exhibiting postprandial hypoglycemia during a meal test. Surg. Obes.Relat. Dis. 14, 929–935. Read more >
Roberts, G. P. et al. (2018) Gastrectomy with Roux-en-Y reconstruction as a lean model of bariatric surgery. Surg. Obes. Relat. Dis. 14, 562–568. Read more >