Precision in cardiometabolic biomarker measurement

Insulin is a cornerstone biomarker in metabolic research. Mercodia offers a range of insulin assays optimized for different sample types and study needs:

• Ultrasensitive Insulin & Insulin ELISA – Ideal for detecting low insulin levels in fasting or postprandial states
• Iso-Insulin ELISA – Differentiates endogenous vs. exogenous insulin
• Lispro ELISA – Designed for detecting Lispro, a fast-acting insulin analogue.
• Insulin & Total Insulin MBeads Assays – High-throughput format for in vitro and perifusion samples

In the fight against obesity, GLP-1 and GIP are key biomarkers. These gastrointestinal peptides regulate satiety, glucose homeostasis, and energy balance, and are central to the development of next-generation weight-loss therapies.

• GLP-1 (Total) ELISA – Chemiluminescent detection of amidated GLP-1 in human plasma and serum
• GIP (Total) ELISA – Quantifies total GIP with no cross-reactivity to GLP-1, glucagon, or related peptides

Glucagon plays a vital role in glucose regulation, especially during fasting. Its secretion is influenced by diet, disease state, and organ interactions.

• Glucagon ELISA – High specificity, minimal matrix interference, and low sample volume requirements, ideal for studies on diabetes, obesity, and hepatic glucose production.

Oxidized LDL is a sensitive marker for atherosclerosis and cardiovascular disease. It is used to add predictive value beyond the traditional lipid profiles.

• OxLDL ELISA – Targets a unique epitope in oxidized ApoB-100, enabling accurate measurement of highly oxidized LDL particles. It is used to strengthen cardiovascular risk models in both basic and clinical research.

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Lipoprotein(a), or Lp(a), is an independent and inherited risk factor for coronary and cerebrovascular disease. Elevated levels are associated with familial hypercholesterolemia and myocardial infarction.

• Lp(a) ELISA – Quantifies Lp(a) in serum or plasma, calibrated against a highly purified commercial preparation, with a detection limit of ≤ 0.07 U/L and no cross-reactivity with plasminogen or ApoB.

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Mercodia’s C-peptide assays support both low-level detection and standard-range quantification, giving researchers flexibility across a wide range of study designs.

• Ultrasensitive C-peptide ELISA – Detects levels below 2.5 pmol/L, validated for serum, plasma, urine, and cell culture media, and ideal for studies in Type 1 diabetes, LADA, and transplantation.
• C-peptide ELISA – Designed for routine quantification of C-peptide in human samples, suitable for clinical and translational research, and offering high specificity with minimal cross-reactivity.

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